MCQs

Question #1: A 45 year old man presents to A&E after developing a severe, sudden-onset headache while bending down at work. He has a background of hypertension but nothing else. He describes the headache as the worst he has ever had. He said that it was worst when it started, and mainly affected the back of his head. On examination his GCS is 15/15 and he has no focal neurological signs. What is the most appropriate initial test?

Question #2: A 37 year old woman presents to neurology clinical with blurred vision. On questioning she says that she is having trouble seeing out of either eye and describes a dull retro-orbital ache whenever she moves the eye. On examining her you notice both pupils are dilated and non-reactive to light. On fundoscopy she has bilaterally swollen optic discs with blurred edges. She has no past medical history of note and has never had anything like this happen to her in the past. What is the most appropriate initial management?

Question #3: What is the mechanism of action of carbidopa?

Question #4: A 38 year old woman comes back to neurology clinic having recently been diagnosed with Huntington’s disease. She has 2 children and is concerned about their risk of developing the disease. Their father is well and has no family history of neurological disease. She carries a mutant huntingtin allele with 45 CAG repeats. What is the chance that her son will develop the disease?

Question #5: A 37 year old woman presents to neurology clinical with blurred vision. On questioning she says that she is having trouble seeing out of either eye and describes a dull retro-orbital ache whenever she moves the eye. On examining her you notice both pupils are dilated and non-reactive to light. On fundoscopy she has bilaterally swollen optic discs with blurred edges. She has no past medical history of note and has never had anything like this happen to her in the past. What is the most likely diagnosis?