Question #1: A 37 year old woman presents to neurology clinical with blurred vision. On questioning she says that she is having trouble seeing out of either eye and describes a dull retro-orbital ache whenever she moves the eye. On examining her you notice both pupils are dilated and non-reactive to light. On fundoscopy she has bilaterally swollen optic discs with blurred edges. She has no past medical history of note and has never had anything like this happen to her in the past. What antibody is most likely to be detectable in her serum?

Question #2: A 30 year old woman presents to A&E with worsening headaches and blurred vision. She reports that her headaches are worst in the morning, exaggerated when she strains, and have been getting worse gradually over weeks. On examination her visual acuity is normal, her extraocular movements are normal, and there is normal tone, power, and reflexes throughout all four limbs. On fundoscopy you notice that she has bilateral papilloedema. She has a BMI of 35, takes the oral contraceptive pill, but has no other medical history of note. What is the most likely diagnosis?

Question #3: What is the mechanism of action of carbidopa?

Question #4: What is the most common cause of a lower motor neuron facial palsy?

Question #5: What would be the characteristic lower limb findings in a Brown-Sequard syndrome?